MathBench > Microbiology

Frank Gets Messy: in search of Exact Doubling Time

Extended problem:
Exponential growth ends (with a whimper)

 

Here's a second set of data on meningococcal growth rates. Your instructions are
1) to determine the exponential growth rate of the bacteria, and
2) to determine when growth stops being exponential.

time popn
0 min 4.3 * 106
20 min 9.7 * 106
40 min 22 * 106
60 min 48 * 106
80 min 97 * 106
100 min 116 * 106
120 min 118 * 106
140 min 67 * 106

 

Just look at the data first... what can you see with your bare eyes, so to speak?

About doubling time:

About the general shape of the population trajectory:

About when growth begins to slow down:

 

Now try plotting the data. (Applet may take several seconds to load).

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Which time period showed exponential growth:

Let's look at an untransformed graph to figure out the doubling time. We could do this on the log-transformed graph above, but its difficult because the y-axis is on a log scale.

graph of untransformed data

Where should we start, and what is the growth rate?